Interleukin 2 Receptor Alpha (IL2RA) Antibody

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor.Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor.Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown.Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.; ; ; ;.

Target	Interleukin 2 Receptor Alpha (IL2RA)
Clonality	Monoclonal
Clone	U100
Reactivity	Human, Mouse, Monkey, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human IL2RA (34-139 AA) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	3559 16184 574300 25704
Molecular Weight	30.8 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 2 Receptor Alpha (IL2RA)

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