Interleukin 34 (IL34) Antibody

Cytokine that promotes the differentiation and viability of monocytes and macrophages.Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.Ligand for colony-stimulating factor-1 receptor CSF1R.Tissue specificity: Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level).Predominantly expressed in spleen.Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

Target	Interleukin 34 (IL34)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human IL34 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q6ZMJ4 (UniProt, ExPASy)
UniProt Secondary AC	B2RC28, B2Z4A8, B2ZC70, Q8N6L2
UniProt Entry Name	IL34_HUMAN
Gene Symbol	IL34
GeneID	146433
OMIM	612081
HGNC	28529
KEGG	hsa:146433
Ensembl	ENSG00000157368
String	9606.ENSP00000397863
Molecular Weight	27.5 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 34 (IL34)

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