Interleukin 6 (IL6) Antibody

IL6 Antibody is a Rabbit Polyclonal antibody against IL6. This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

Target	Interleukin 6 (IL6)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 30-212 of human IL6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05231 (UniProt, ExPASy)
UniProt Secondary AC	Q9UCU2, Q9UCU3, Q9UCU4
UniProt Entry Name	IL6_HUMAN
Gene Symbol	IL6
GeneID	3569
NCBI Accession	NP_000591.1
KEGG	hsa:3569
String	9606.ENSP00000385675
Molecular Weight	Calculated MW: 24 kDa Observed MW: 24 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	4.69 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 6 (IL6)

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