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Interleukin 7 Receptor (IL7R) Antibody

Catalogue No: abx001142
Price: £120.00
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Interleukin 7 Receptor (IL7R) Antibody

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IL7R Antibody is a Rabbit Polyclonal antibody against IL7R. The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008].

Target Interleukin 7 Receptor (IL7R)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human IL7R.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16871 (UniProt, ExPASy)
UniProt Entry Name IL7RA_HUMAN
Gene Symbol IL7R
GeneID 3575
String 9606.ENSP00000306157
Molecular Weight Calculated MW: 28 kDa, 29 kDa, 34 kDa, 51 kDa
Observed MW: 52 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Interleukin 7 Receptor (IL7R) Antibody

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