Integrin-Linked Protein Kinase (ILK) Antibody

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

Target	Integrin-Linked Protein Kinase (ILK)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 225-253 amino acids from human ILK.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13418 (UniProt, ExPASy)
UniProt Secondary AC	B7Z1I0, B7Z418, D3DQU0, P57043, Q68DZ3
UniProt Entry Name	ILK_HUMAN
Gene Symbol	ILK
GeneID	3611
OMIM	602366
HGNC	6040
KEGG	hsa:3611
Ensembl	ENSG00000166333
String	9606.ENSP00000379975
Enzyme Commission Number	EC 2.7.11.1
Molecular Weight	Calculated MW: 51.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Cow ILK.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Integrin-Linked Protein Kinase (ILK)

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