Integrin-Linked Protein Kinase (ILK) Antibody

ILK Antibody is a Rabbit Polyclonal antibody against ILK. This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.

Target	Integrin-Linked Protein Kinase (ILK)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ILK.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13418 (UniProt, ExPASy)
UniProt Secondary AC	B7Z1I0, B7Z418, D3DQU0, P57043, Q68DZ3
UniProt Entry Name	ILK_HUMAN
Gene Symbol	ILK
GeneID	3611
OMIM	602366
NCBI Accession	NP_001014795.1
HGNC	6040
KEGG	hsa:3611
Ensembl	ENSG00000166333
String	9606.ENSP00000379975
Enzyme Commission Number	EC 2.7.11.1
Molecular Weight	Calculated MW: 51 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Integrin-Linked Protein Kinase (ILK)

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