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Integrin-Linked Protein Kinase Phospho-Ser246 (ILK pS246) Antibody
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Catalogue No: abx032016
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
Research Articles on Integrin-Linked Protein Kinase Phospho-Ser246 (ILK pS246)
| Target | Integrin-Linked Protein Kinase Phospho-Ser246 (ILK pS246) |
| Clonality | Polyclonal |
| Target Modification | Ser246 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S246 of human ILK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13418 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z1I0, B7Z418, D3DQU0, P57043, Q68DZ3 |
| UniProt Entry Name | ILK_HUMAN |
| Gene Symbol | ILK |
| GeneID | 3611 |
| OMIM | 602366 |
| HGNC | 6040 |
| KEGG | hsa:3611 |
| Ensembl | ENSG00000166333 |
| String | 9606.ENSP00000379975 |
| Enzyme Commission Number | EC 2.7.11.1 |
| Molecular Weight | Calculated MW: 51.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow ILK. |
| Availability | Please enquire. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |