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Indoleamine 2,3-Dioxygenase 1 (INDO) Antibody

Catalogue No: abx001358
Price: £120.00
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Indoleamine 2,3-Dioxygenase 1 (INDO) Antibody

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INDO Antibody is a Rabbit Polyclonal antibody against INDO. This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

Target INDO
Clonality Polyclonal
Reactivity Human, Mouse, Monkey
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human INDO.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P14902 (UniProt, ExPASy)
UniProt Secondary AC E5RGR8, F6M9T7, Q540B4
Gene Symbol IDO1
GeneID 3620
Molecular Weight Calculated MW: 45 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Indoleamine 2,3-Dioxygenase 1 (INDO) Antibody

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