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Insulin (INS) Antibody

Catalogue No: abx001702
Price: £120.00
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Insulin (INS) Antibody

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INS Antibody is a Rabbit Polyclonal antibody against INS. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Target INS
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human INS.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01308 (UniProt, ExPASy)
UniProt Secondary AC Q5EEX2
UniProt Entry Name INS_HUMAN
Gene Symbol INS
GeneID 3630
KEGG hsa:3630
String 9606.ENSP00000380432
Molecular Weight Calculated MW: 11 kDa, 21 kDa
Observed MW: 12 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Insulin (INS) Antibody

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