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Insulin Receptor (INSR) Antibody
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Catalogue No: abx000670
Price:
US$203.00
(Size: 20 µl)
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INSR Antibody is a Rabbit Polyclonal antibody against INSR. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Insulin Receptor (INSR)
| Target | Insulin Receptor (INSR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1130-1230 of human Insulin Receptor. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06213 (UniProt, ExPASy) |
| UniProt Secondary AC | Q17RW0, Q59H98, Q9UCB7, Q9UCB8, Q9UCB9 |
| UniProt Entry Name | INSR_HUMAN |
| Gene Symbol | INSR |
| GeneID | 3643 |
| OMIM | 125853 |
| NCBI Accession | NP_000199.2 |
| HGNC | 6091 |
| KEGG | hsa:3643 |
| Ensembl | ENSG00000171105 |
| String | 9606.ENSP00000303830 |
| Enzyme Commission Number | EC 2.7.10.1 |
| Molecular Weight | Calculated MW: 156 kDa Observed MW: 95/220 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
