Insulin Receptor (INSR) Antibody
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Catalogue No: abx000670
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US$348.00
(Size: 60 µl)
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Datasheet SDS
INSR Antibody is a Rabbit Polyclonal antibody against INSR. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Insulin Receptor (INSR)
| Target | Insulin Receptor (INSR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human INSR |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06213 (UniProt, ExPASy) |
| UniProt Secondary AC | Q17RW0, Q59H98, Q9UCB7, Q9UCB8, Q9UCB9 |
| UniProt Entry Name | INSR_HUMAN |
| Gene Symbol | INSR |
| GeneID | 3643 |
| OMIM | 125853 |
| NCBI Accession | NP_000199.2 |
| HGNC | 6091 |
| KEGG | hsa:3643 |
| Ensembl | ENSG00000171105 |
| String | 9606.ENSP00000303830 |
| Enzyme Commission Number | EC 2.7.10.1 |
| Molecular Weight | Calculated MW: 155 kDa/156 kDa Observed MW: 110 kDa/220 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
