Insulin-Like Growth Factor-Binding Protein 2 (IGFBP2) Antibody
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Catalogue No: abx010964
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Insulin Like Growth Factor Binding Protein 2 (IGFBP2): insulin-like growth factor binding protein 2. Insulin Like Growth Factor Binding Protein 2 (IGFBP2) is a member of the ISGBP family which bind various IGFs. Insulin Like Growth Factor Binding Protein 2 (IGFBP2) is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of Insulin Like Growth Factor Binding Protein 2 (IGFBP2) also correlates with the aggressiveness of some tumors. Insulin Like Growth Factor Binding Protein 2 (IGFBP2) activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
Research Articles on Insulin-Like Growth Factor-Binding Protein 2 (IGFBP2)
| Target | Insulin-Like Growth Factor-Binding Protein 2 (IGFBP2) |
| Research Area | Tumor Immunity, Endocrinology, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P18065 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14619, Q9UCL3 |
| UniProt Entry Name | IBP2_HUMAN |
| Gene Symbol | IGFBP2 |
| GeneID | 3485 |
| OMIM | 146731 |
| HGNC | 5471 |
| KEGG | hsa:3485 |
| Ensembl | ENSG00000115457 |
| String | 9606.ENSP00000233809 |
| Molecular Weight | 35 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |