Integrin Alpha-L (ITGAL) Antibody (PE)

Integrin Alpha-L (ITGAL) Antibody (PE) is an antibody against Integrin Alpha-L (ITGAL). ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Target	Integrin Alpha-L (ITGAL)
Clone	C874
Reactivity	Human
Tested Applications	FCM
Host	Mouse
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	PE
Isotype	IgG1
Purification	The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Storage	Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
UniProt Primary AC	P20701 (UniProt, ExPASy)
Gene Symbol	ITGAL
GeneID	3683
Buffer	Stabilizing PBS solution containing 15 mM sodium azide.
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Integrin Alpha-L (ITGAL)

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