Integrin Alpha M / CD11b (ITGAM) Antibody

Catalogue No: abx001331
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
Integrin alpha M (ITGAM) Antibody is a Rabbit Polyclonal antibody against Integrin alpha M (ITGAM). Integrin alpha M (ITGAM), also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Integrin alpha M (ITGAM) is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. It is also a receptor for fibrinogen, factor X and ICAM1. Integrin alpha M (ITGAM) recognizes P1 and P2 peptides of fibrinogen gamma chain.

Target Integrin Alpha M / CD11b (ITGAM)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ITGAM.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P11215 (UniProt, ExPASy)
UniProt Secondary AC Q4VAK0, Q4VAK1, Q4VAK2
UniProt Entry Name ITAM_HUMAN
Gene Symbol ITGAM
GeneID 3684
KEGG hsa:3684
String 9606.ENSP00000441691
Molecular Weight Calculated MW: 127 kDa
Observed MW: 180 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Integrin Alpha M / CD11b (ITGAM)

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