Integrin Alpha M / CD11b (ITGAM) Antibody
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Catalogue No: abx001331
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US$348.00
(Size: 60 µl)
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Datasheet SDS
Integrin alpha M (ITGAM) Antibody is a Rabbit Polyclonal antibody against Integrin alpha M (ITGAM). Integrin alpha M (ITGAM), also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Integrin alpha M (ITGAM) is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. It is also a receptor for fibrinogen, factor X and ICAM1. Integrin alpha M (ITGAM) recognizes P1 and P2 peptides of fibrinogen gamma chain.
Research Articles on Integrin Alpha M / CD11b (ITGAM)
| Target | Integrin Alpha M / CD11b (ITGAM) |
| Research Area | Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Immunology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CD11B |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P11215 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4VAK0, Q4VAK1, Q4VAK2 |
| UniProt Entry Name | ITAM_HUMAN |
| Gene Symbol | ITGAM |
| GeneID | 3684 |
| NCBI Accession | NP_000623.2 |
| KEGG | hsa:3684 |
| String | 9606.ENSP00000441691 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
