Integrin Alpha-E / CD103 (ITGAE) Antibody

Integrin Alpha-E / CD103 (ITGAE) Antibody is a Rabbit Polyclonal antibody for the detection of ITGAE.

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

Target	Integrin Alpha-E / CD103 (ITGAE)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	ITGAE
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P38570 (UniProt, ExPASy)
UniProt Secondary AC	Q17RS6, Q9NZU9
UniProt Entry Name	ITAE_HUMAN
Gene Symbol	ITGAE
GeneID	3682
OMIM	604682
HGNC	6147
KEGG	hsa:3682
Ensembl	ENSG00000083457
String	9606.ENSP00000263087
Molecular Weight	Observed MW: 110 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Integrin Alpha-E / CD103 (ITGAE)

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