Interleukin 1 Beta (IL1B) Antibody

Interleukin 1 Beta (IL1B) Antibody is a Rabbit Polyclonal antibody for the detection of IL1 beta.

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Target	Interleukin 1 Beta (IL1B)
Clonality	Polyclonal
Reactivity	Rat
Tested Applications	ELISA, IHC
Host	Rabbit
Recommended dilutions	IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	interleukin 1, beta
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q63264 (UniProt, ExPASy)
Gene Symbol	IL1B
GeneID	24494
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Interleukin 1 Beta (IL1B)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue