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Interleukin 2 Receptor Alpha (IL2RA) Antibody
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Catalogue No: abx239909
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Interleukin 2 Receptor Alpha (IL2RA) Antibody is a Rabbit Polyclonal antibody for the detection of IL2RA. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Research Articles on Interleukin 2 Receptor Alpha (IL2RA)
| Target | Interleukin 2 Receptor Alpha (IL2RA) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | IL2RA |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01589 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5W007 |
| UniProt Entry Name | IL2RA_HUMAN |
| Gene Symbol | IL2RA |
| GeneID | 3559 |
| OMIM | 147730 |
| HGNC | 6008 |
| KEGG | hsa:3559 |
| Ensembl | ENSG00000134460 |
| String | 9606.ENSP00000369293 |
| Molecular Weight | Observed MW: 30 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |