Importin-5 (IPO5) Antibody

Catalogue No: abx001616
Price: £120.00
(Size: 20 µl)
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Importin-5 (IPO5) Antibody Importin-5 (IPO5) Antibody

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IPO5 Antibody is a Rabbit Polyclonal antibody against IPO5. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Target IPO5
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human IPO5.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O00410 (UniProt, ExPASy)
UniProt Secondary AC B4DZA0, O15257, Q5T578, Q86XC7
UniProt Entry Name IPO5_HUMAN
Gene Symbol IPO5
GeneID 3843
KEGG hsa:3843
String 9606.ENSP00000261574
Molecular Weight Calculated MW: 116 kDa, 123 kDa, 125 kDa
Observed MW: 125 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Importin-5 (IPO5) Antibody

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