Interleukin-1 Receptor Associated Kinase 3 (IRAK3) Antibody

Interleukin-1 Receptor Associated Kinase 3 (IRAK3) Antibody is a Rabbit Polyclonal antibody for the detection of IRAK-3.

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.

Target	Interleukin-1 Receptor Associated Kinase 3 (IRAK3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	IRAK3
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q9Y616 (UniProt, ExPASy)
UniProt Secondary AC	B4DQ57
UniProt Entry Name	IRAK3_HUMAN
Gene Symbol	IRAK3
GeneID	11213
OMIM	604459
HGNC	17020
Ensembl	ENSG00000090376
String	9606.ENSP00000261233
Molecular Weight	Observed MW: 68 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Interleukin-1 Receptor Associated Kinase 3 (IRAK3)

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