Interferon Regulatory Factor 3 (IRF3) Antibody

Catalogue No: abx000868
Price: £120.00
(Size: 20 µl)
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IRF3 Antibody is a Rabbit Polyclonal antibody against IRF3. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Target IRF3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human IRF-3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q14653 (UniProt, ExPASy)
UniProt Secondary AC A8K7L2, B2RAZ3, Q5FBY1, Q5FBY2, Q5FBY4, Q7Z5G6
UniProt Entry Name IRF3_HUMAN
Gene Symbol IRF3
GeneID 3661
KEGG hsa:3661
String 9606.ENSP00000471896
Molecular Weight Calculated MW: 12 kDa, 16 kDa, 33 kDa, 47 kDa, 49 kDa
Observed MW: 47 kDa, 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on IRF3

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