Interferon Regulatory Factor 3 (IRF3) Antibody
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Catalogue No: abx001784
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US$217.50
(Size: 20 µl)
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Datasheet SDS
IRF3 Antibody is a Rabbit Polyclonal antibody against IRF3. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Research Articles on Interferon Regulatory Factor 3 (IRF3)
| Target | Interferon Regulatory Factor 3 (IRF3) |
| Research Area | Infection Immunity, Immunology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human IRF3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q14653 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7L2, B2RAZ3, Q5FBY1, Q5FBY2, Q5FBY4, Q7Z5G6 |
| UniProt Entry Name | IRF3_HUMAN |
| Gene Symbol | IRF3 |
| GeneID | 3661 |
| NCBI Accession | NP_001184052.1 |
| KEGG | hsa:3661 |
| String | 9606.ENSP00000471896 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 45-55 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | 1.76 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |