Interferon Regulatory Factor 3 (IRF3) Antibody

IRF3 Antibody is a Rabbit Polyclonal antibody against IRF3. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Target	Interferon Regulatory Factor 3 (IRF3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human IRF3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14653 (UniProt, ExPASy)
UniProt Secondary AC	A8K7L2, B2RAZ3, Q5FBY1, Q5FBY2, Q5FBY4, Q7Z5G6
UniProt Entry Name	IRF3_HUMAN
Gene Symbol	IRF3
GeneID	3661
NCBI Accession	NP_001184052.1
KEGG	hsa:3661
String	9606.ENSP00000471896
Molecular Weight	Calculated MW: 47 kDa Observed MW: 45-55 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1.76 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interferon Regulatory Factor 3 (IRF3)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue