Interferon Regulatory Factor 4 (IRF4) Antibody

IRF4 Antibody is a Rabbit Polyclonal antibody against IRF4. Interferon regulatory factor 4 (IRF4) is a member of the IRF family of transcription factors, expressed in most cell types of the immune system. IRF4 is a transcription factor essential for the development of T helper-2 (Th2) cells, IL17-producing Th17 cells, and IL9-producing Th9 cells, as well as dendritic cell (DC). It binds to and activates the interferon-stimulated response element (ISRE) of the MHC class I promoter, and may have a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.

Target	Interferon Regulatory Factor 4 (IRF4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 150-350 of human IRF4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15306 (UniProt, ExPASy)
UniProt Secondary AC	Q5VUI7, Q99660
UniProt Entry Name	IRF4_HUMAN
Gene Symbol	IRF4
GeneID	3662
NCBI Accession	NP_002451.2
KEGG	hsa:3662
String	9606.ENSP00000370343
Molecular Weight	Calculated MW: 52 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interferon Regulatory Factor 4 (IRF4)

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