Interferon Regulatory Factor 4 (IRF4) Antibody

Catalogue No: abx000976
Price: £120.00
(Size: 20 µl)
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IRF4 Antibody is a Rabbit Polyclonal antibody against IRF4. The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Target IRF4
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human IRF4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15306 (UniProt, ExPASy)
UniProt Secondary AC Q5VUI7, Q99660
UniProt Entry Name IRF4_HUMAN
Gene Symbol IRF4
GeneID 3662
KEGG hsa:3662
String 9606.ENSP00000370343
Molecular Weight Calculated MW: 51 kDa
Observed MW: 52 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Interferon Regulatory Factor 4 (IRF4) Antibody

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