Ubiquitin-Like Protein ISG15 (ISG15) Antibody

ISG15 Antibody is a Rabbit Polyclonal antibody against ISG15. The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.

Target	Ubiquitin-Like Protein ISG15 (ISG15)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05161 (UniProt, ExPASy)
UniProt Secondary AC	Q5SVA4, Q7Z2G2, Q96GF0
UniProt Entry Name	ISG15_HUMAN
Gene Symbol	ISG15
GeneID	9636
NCBI Accession	NP_005092.1
KEGG	hsa:9636
String	9606.ENSP00000368699
Molecular Weight	Calculated MW: 18 kDa Observed MW: 15 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin-Like Protein ISG15 (ISG15)

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