Insulin Gene Enhancer Protein ISL-1 (ISL1) Antibody

Catalogue No: abx015896
Price: £290.00
(Size: 100 µl)

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Datasheet SDS
ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors.It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression.It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation.Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.Mutations in this gene have been associated with maturity-onset diabetes of the young.

Target ISL1
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IF/ICC
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human ISL1 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P61371 (UniProt, ExPASy)
UniProt Secondary AC P20663, P47894
UniProt Entry Name ISL1_HUMAN
Gene Symbol ISL1
GeneID 3670
OMIM 600366
HGNC 6132
KEGG hsa:3670
Ensembl ENSG00000016082
String 9606.ENSP00000230658
Molecular Weight 39 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ISL1

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