Integrin Alpha IIb / CD41 (ITGA2B) Antibody

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Catalogue No: abx015897
Price: US$427.75
(Size: 100 µl)

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Integrin Alpha IIb / CD41 (ITGA2B) Antibody Integrin Alpha IIb / CD41 (ITGA2B) Antibody Integrin Alpha IIb / CD41 (ITGA2B) Antibody Integrin Alpha IIb / CD41 (ITGA2B) Antibody Integrin Alpha IIb / CD41 (ITGA2B) Antibody

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Datasheet SDS
ITGA2B encodes integrin alpha chain 2b.Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation.Mutations that interfere with this role result in thrombasthenia.In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Target Integrin Alpha IIb / CD41 (ITGA2B)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P08514 (UniProt, ExPASy)
UniProt Secondary AC B2RCY8, O95366, Q14443, Q17R67
UniProt Entry Name ITA2B_HUMAN
Gene Symbol ITGA2B
GeneID 3674
OMIM 187800
HGNC 6138
KEGG hsa:3674
Ensembl ENSG00000005961
String 9606.ENSP00000262407
Molecular Weight 113.4 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Integrin Alpha IIb / CD41 (ITGA2B)


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