Integrin Alpha 5 (ITGA5) Antibody

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq].

Target	Integrin Alpha 5 (ITGA5)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 575-602 amino acids from the Central region of human ITGA5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P08648 (UniProt, ExPASy)
UniProt Secondary AC	Q96HA5
UniProt Entry Name	ITA5_HUMAN
KEGG	hsa:3678
String	9606.ENSP00000293379
Molecular Weight	Calculated MW: 115 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse ITGA5.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Integrin Alpha 5 (ITGA5)

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