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Integrin Alpha-L (ITGAL) Antibody
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Catalogue No: abx001384
Price:
£120.00
(Size: 20 µl)
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ITGAL Antibody is a Rabbit Polyclonal antibody against ITGAL. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Integrin Alpha-L (ITGAL)
| Target | Integrin Alpha-L (ITGAL) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human ITGAL. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20701 (UniProt, ExPASy) |
| UniProt Secondary AC | O43746, Q45H73, Q96HB1, Q9UBC8 |
| UniProt Entry Name | ITAL_HUMAN |
| Gene Symbol | ITGAL |
| GeneID | 3683 |
| KEGG | hsa:3683 |
| String | 9606.ENSP00000349252 |
| Molecular Weight | Calculated MW: 119 kDa, 128 kDa, 134 kDa Observed MW: 180 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
