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Integrin Alpha-L (ITGAL) Antibody

Catalogue No: abx001384
Price: £120.00
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Integrin Alpha-L (ITGAL) Antibody

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ITGAL Antibody is a Rabbit Polyclonal antibody against ITGAL. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Target Integrin Alpha-L (ITGAL)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ITGAL.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20701 (UniProt, ExPASy)
UniProt Secondary AC O43746, Q45H73, Q96HB1, Q9UBC8
UniProt Entry Name ITAL_HUMAN
Gene Symbol ITGAL
GeneID 3683
KEGG hsa:3683
String 9606.ENSP00000349252
Molecular Weight Calculated MW: 119 kDa, 128 kDa, 134 kDa
Observed MW: 180 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Integrin Alpha-L (ITGAL) Antibody

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