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Integrin Alpha V (ITGAV) Antibody

Catalogue No: abx001703
Price: £120.00
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Integrin Alpha V (ITGAV) Antibody Integrin Alpha V (ITGAV) Antibody Integrin Alpha V (ITGAV) Antibody

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ITGAV Antibody is a Rabbit Polyclonal antibody against ITGAV. This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. Note that the integrin alpha 5 and integrin alpha V chains are produced by distinct genes.

Target ITGAV
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human ITGAV.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P06756 (UniProt, ExPASy)
UniProt Entry Name ITAV_HUMAN
Gene Symbol ITGAV
GeneID 3685
KEGG hsa:3685
String 9606.ENSP00000261023
Molecular Weight Calculated MW: 111 kDa, 112 kDa, 116 kDa
Observed MW: 140 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Integrin Alpha V (ITGAV) Antibody

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