Nicotinamide Riboside Kinase 2 / ITGB1BP3 (NMRK2) Antibody

NMRK2/ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.

Target	Nicotinamide Riboside Kinase 2 / ITGB1BP3 (NMRK2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITGB1BP3.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NPI5 (UniProt, ExPASy)
UniProt Secondary AC	B7ZKR3, Q52M81, Q9NZK3
UniProt Entry Name	NRK2_HUMAN
Gene Symbol	NMRK2
GeneID	27231
OMIM	608705
KEGG	hsa:27231
Ensembl	ENSG00000077009
String	9606.ENSP00000480091
Molecular Weight	Calculated MW: 26 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse NMRK2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nicotinamide Riboside Kinase 2 / ITGB1BP3 (NMRK2)

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