Integrin Beta 2 (ITGB2) Antibody
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Catalogue No: abx030025
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Research Articles on Integrin Beta 2 (ITGB2)
| Target | Integrin Beta 2 (ITGB2) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein encoding human ITGB2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P05107 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KTS8, D3DSM1, Q16418, Q53HS5, Q9UD72 |
| UniProt Entry Name | ITB2_HUMAN |
| KEGG | hsa:3689 |
| String | 9606.ENSP00000380948 |
| Molecular Weight | Calculated MW: 84.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |