Integrin Beta 2 (ITGB2) Antibody

ITGB2 Antibody is a Rabbit Polyclonal antibody against ITGB2. This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

Target	Integrin Beta 2 (ITGB2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 23-125 of CD18.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05107 (UniProt, ExPASy)
UniProt Secondary AC	B3KTS8, D3DSM1, Q16418, Q53HS5, Q9UD72
UniProt Entry Name	ITB2_HUMAN
Gene Symbol	ITGB2
GeneID	3689
NCBI Accession	NP_000202.3
KEGG	hsa:3689
String	9606.ENSP00000380948
Molecular Weight	Calculated MW: 85 kDa Observed MW: 95 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Integrin Beta 2 (ITGB2)

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