Integrin Beta 4 (ITGb4) Antibody

Catalogue No: abx000880
Price: £120.00
(Size: 20 µl)
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Integrin Beta 4 (ITGb4) Antibody

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ITGB4 Antibody is a Rabbit Polyclonal antibody against ITGB4. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Target Integrin Beta 4 (ITGb4)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ITGB4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16144 (UniProt, ExPASy)
UniProt Entry Name ITB4_HUMAN
Gene Symbol ITGB4
GeneID 3691
KEGG hsa:3691
String 9606.ENSP00000200181
Molecular Weight Calculated MW: 106 kDa, 194 kDa, 195 kDa, 200 kDa, 202 kDa
Observed MW: 220 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Integrin Beta 4 (ITGb4) Antibody

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