J9

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Catalogue No: abx076815
Price: US$435.00
(Size: 10 mg)

Orders to United States ship from United States

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J9

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Datasheet SDS
J9 is a small molecule. J9, in combination with dexamethasone inhibits cell growth in T-cell acute lymphoblastic leukemia (T-ALL) through the upregulation of the glucocorticoid receptor. Patients can develop glucocorticoid resistance rendering the treatment ineffective. J9 and its mechanism of action provides a useful strategy for overcoming the resistance. The EC50 of J9 in combination with dexamethasone is 28 uM. J9 alone was less toxic.

Target J9
Origin Synthetic
Form Solid
Purity 0.999
Storage Store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life 12 months.
Molecular Weight 212.26 g/mol
Molecular Formula C12H12N4
SMILES NC1=NC(C2CC2)=C(C3=CC=NC=C3)C=N1
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on J9


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