Tyrosine-Protein Kinase JAK2 Phospho-Tyr221 (JAK2 pY221) Antibody

Tyrosine-Protein Kinase JAK2 Phospho-Tyr221 (JAK2 pY221) Antibody is a Rabbit Polyclonal antibody against Tyrosine-Protein Kinase JAK2 Phospho-Tyr221 (JAK2 pY221). This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Target	Tyrosine-Protein Kinase JAK2 Phospho-Tyr221 (JAK2 pY221)
Clonality	Polyclonal
Target Modification	Tyr221
Modification	Phosphorylation
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around Y221 of human JAK2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O60674 (UniProt, ExPASy)
UniProt Secondary AC	O14636, O75297
UniProt Entry Name	JAK2_HUMAN
Gene Symbol	JAK2
GeneID	3717
NCBI Accession	NP_004963.1
KEGG	hsa:3717
String	9606.ENSP00000371067
Molecular Weight	Calculated MW: 131 kDa Observed MW: 125 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tyrosine-Protein Kinase JAK2 Phospho-Tyr221 (JAK2 pY221)

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