Junctional Adhesion Molecule 2 (JAM2) Antibody
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Catalogue No: abx027880
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq].
Research Articles on Junctional Adhesion Molecule 2 (JAM2)
| Target | Junctional Adhesion Molecule 2 (JAM2) |
| Research Area | Cellular Differentiation and Adhesion, Enzymes and Kinases, Tumor Immunity, Infection Immunity, Immunology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human JAM2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P57087 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6T9, B4DGT9, Q6UXG6, Q6YNC1 |
| UniProt Entry Name | JAM2_HUMAN |
| KEGG | hsa:58494 |
| String | 9606.ENSP00000383376 |
| Molecular Weight | Calculated MW: 33.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |