Junction Plakoglobin (JUP) Antibody
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Catalogue No: abx011985
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
Research Articles on Junction Plakoglobin (JUP)
| Target | Junction Plakoglobin (JUP) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human JUP expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P14923 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9 |
| UniProt Entry Name | PLAK_HUMAN |
| Gene Symbol | JUP |
| GeneID | 3728 |
| OMIM | 173325 |
| HGNC | 6207 |
| KEGG | hsa:3728 |
| Ensembl | ENSG00000173801 |
| String | 9606.ENSP00000377508 |
| Molecular Weight | 82 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |