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Junction Plakoglobin (JUP) Antibody
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Catalogue No: abx025491
Price:
US$623.50
(Size: 100 µl)
Orders to United States ship from United States
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This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. This antibody is supplied as crude ascites.
Research Articles on Junction Plakoglobin (JUP)
| Target | Junction Plakoglobin (JUP) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/1600. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 636-663 amino acids from human JUP. |
| Isotype | IgG3 |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14923 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9 |
| UniProt Entry Name | PLAK_HUMAN |
| Gene Symbol | JUP |
| GeneID | 3728 |
| OMIM | 173325 |
| HGNC | 6207 |
| KEGG | hsa:3728 |
| Ensembl | ENSG00000173801 |
| String | 9606.ENSP00000377508 |
| Molecular Weight | Calculated MW: 81.7 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Pig JUP. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |