Junction Plakoglobin (JUP) Antibody
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Catalogue No: abx034189
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US$326.25
(Size: 80 µl)
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Datasheet SDS
JUP is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
Research Articles on Junction Plakoglobin (JUP)
| Target | Junction Plakoglobin (JUP) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 636-663 amino acids from the C-terminal region of human JUP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P14923 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9 |
| UniProt Entry Name | PLAK_HUMAN |
| Gene Symbol | JUP |
| GeneID | 3728 |
| OMIM | 173325 |
| HGNC | 6207 |
| KEGG | hsa:3728 |
| Ensembl | ENSG00000173801 |
| String | 9606.ENSP00000377508 |
| Molecular Weight | Calculated MW: 81.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Pig JUP. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |