Kelch Repeat And BTB Domain-Containing Protein 3 (KBTBD3) Antibody

KBTBD3 Antibody is a Rabbit Polyclonal antibody against KBTBD3. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Target	Kelch Repeat And BTB Domain-Containing Protein 3 (KBTBD3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 410-607 of mouse KBTBD3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8NAB2 (UniProt, ExPASy)
UniProt Secondary AC	Q6N066, Q86X38, Q96NK5
UniProt Entry Name	KBTB3_HUMAN
Gene Symbol	KBTBD3
GeneID	143879
NCBI Accession	NP_081238.2
KEGG	hsa:143879
String	9606.ENSP00000436262
Molecular Weight	Calculated MW: 69 kDa Observed MW: 69 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kelch Repeat And BTB Domain-Containing Protein 3 (KBTBD3)

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