Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2) Antibody

KCNA2 Antibody is a Rabbit Polyclonal antibody against KCNA2. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Target	Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human KCNA2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P16389 (UniProt, ExPASy)
UniProt Secondary AC	A0A024R0D3, A8K1Z6, Q86XG6
UniProt Entry Name	KCNA2_HUMAN
Gene Symbol	KCNA2
GeneID	3737
NCBI Accession	NP_004965.1
KEGG	hsa:3737
String	9606.ENSP00000433109
Molecular Weight	Calculated MW: 57 kDa Observed MW: 60 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2)

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