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Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody

Catalogue No: abx002160
Price: £120.00
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Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody

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KCNH2 Antibody is a Rabbit Polyclonal antibody against KCNH2. This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.

Target KCNH2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human KCNH2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q12809 (UniProt, ExPASy)
UniProt Entry Name KCNH2_HUMAN
Gene Symbol KCNH2
GeneID 3757
KEGG hsa:3757
String 9606.ENSP00000262186
Molecular Weight Calculated MW: 60 kDa, 90 kDa, 97 kDa, 115 kDa, 121 kDa, 126 kDa
Observed MW: 148 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody

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