Potassium Inwardly Rectifying Channel Subfamily J, Member 1 (KCNJ1) Antibody

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Potassium Inwardly Rectifying Channel Subfamily J, Member 1 (KCNJ1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human KCNJ1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P48048 (UniProt, ExPASy)
UniProt Secondary AC	B2RMR4, Q6LD67
UniProt Entry Name	KCNJ1_HUMAN
KEGG	hsa:3758
String	9606.ENSP00000376432
Molecular Weight	Calculated MW: 44.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Potassium Inwardly Rectifying Channel Subfamily J, Member 1 (KCNJ1)

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