Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) Antibody
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Catalogue No: abx015902
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential.This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3.Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation.This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others.This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS.Alternatively spliced transcript variants have been found for this gene.
Research Articles on Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1)
| Target | Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human KCNQ1 expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P51787 (UniProt, ExPASy) |
| UniProt Entry Name | KCNQ1_HUMAN |
| Gene Symbol | KCNQ1 |
| GeneID | 3784 |
| OMIM | 125853 |
| HGNC | 6294 |
| KEGG | hsa:3784 |
| Ensembl | ENSG00000053918 |
| String | 9606.ENSP00000155840 |
| Molecular Weight | 95 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |