Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) Antibody

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Catalogue No: abx015902
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential.This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3.Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation.This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others.This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS.Alternatively spliced transcript variants have been found for this gene.

Target Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human KCNQ1 expressed in E. coli.
Isotype IgG2b
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P51787 (UniProt, ExPASy)
UniProt Entry Name KCNQ1_HUMAN
Gene Symbol KCNQ1
GeneID 3784
OMIM 125853
HGNC 6294
KEGG hsa:3784
Ensembl ENSG00000053918
String 9606.ENSP00000155840
Molecular Weight 95 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1)


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