Lysine-Specific Demethylase 3A (KDM3A) Antibody

Catalogue No: abx001885
Price: £120.00
(Size: 20 µl)
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KDM3A Antibody is a Rabbit Polyclonal antibody against KDM3A. KDM3A, also name as JMJD1A, JHDM2A, JMJD1, JMJD1A, KIAA0742 and TSGA, belongs to the JHDM2 histone demethylase family. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It is involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. It is involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1. (PubMed:16603237), JMJD1A is a useful biomarker for hypoxic tumor cells and a prognostic marker that could be a promising therapeutic target against CRC. (PMID:20823141) This antibody recognize the N-term of KDM3A(JMJD1A).

Target KDM3A
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human KDM3A.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y4C1 (UniProt, ExPASy)
UniProt Secondary AC D6W5M3, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08
UniProt Entry Name KDM3A_HUMAN
Gene Symbol KDM3A
GeneID 55818
String 9606.ENSP00000386660
Molecular Weight Calculated MW: 147 kDa
Observed MW: 157 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on KDM3A

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