Lysine Demethylase 6B (KDM6B) Antibody
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Catalogue No: abx029510
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Research Articles on Lysine Demethylase 6B (KDM6B)
| Target | Lysine Demethylase 6B (KDM6B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 167-195 amino acids from the N-terminal region of human KDM6B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15054 (UniProt, ExPASy) |
| UniProt Secondary AC | C9IZ40, Q96G33 |
| UniProt Entry Name | KDM6B_HUMAN |
| Gene Symbol | KDM6B |
| KEGG | hsa:23135 |
| String | 9606.ENSP00000254846 |
| Molecular Weight | Calculated MW: 177 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |