Kinase Insert Domain Receptor (KDR) Antibody
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Catalogue No: abx012344
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US$427.75
(Size: 100 µl)
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Datasheet SDS
VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability.
Research Articles on Kinase Insert Domain Receptor (KDR)
| Target | Kinase Insert Domain Receptor (KDR) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35968 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RRS0, B5A925, C5IFA0, O60723, Q14178 |
| UniProt Entry Name | VGFR2_HUMAN |
| Gene Symbol | KDR |
| GeneID | 3791 |
| OMIM | 191306 |
| HGNC | 6307 |
| KEGG | hsa:3791 |
| Ensembl | ENSG00000128052 |
| String | 9606.ENSP00000263923 |
| Enzyme Commission Number | EC 2.7.10.1 |
| Molecular Weight | 152 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |