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KDR (pY1175) Antibody
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Catalogue No: abx000430
Price:
US$232.00
(Size: 20 µl)
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KDR (pY1175) Antibody is a Rabbit Polyclonal antibody against KDR (pY1175). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.
Research Articles on KDR (pY1175)
| Target | KDR (pY1175) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to KDR (pY1175). The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35968 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RRS0, B5A925, C5IFA0, O60723, Q14178 |
| UniProt Entry Name | VGFR2_HUMAN |
| Gene Symbol | KDR |
| GeneID | 3791 |
| NCBI Accession | NP_002244.1 |
| KEGG | hsa:3791 |
| String | 9606.ENSP00000263923 |
| Molecular Weight | Calculated MW: 152 kDa Observed MW: 230 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1.72 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |