KDR (pY1175) Antibody

Catalogue No: abx000430
Price: £230.00
(Size: 50 µl)
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KDR (pY1175) Antibody is a Rabbit Polyclonal antibody against KDR (pY1175). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.

Target KDR (pY1175)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y1175 of human KDR.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35968 (UniProt, ExPASy)
UniProt Secondary AC A2RRS0, B5A925, C5IFA0, O60723, Q14178
UniProt Entry Name VGFR2_HUMAN
Gene Symbol KDR
GeneID 3791
KEGG hsa:3791
String 9606.ENSP00000263923
Molecular Weight Calculated MW: 75 kDa, 79 kDa, 151 kDa
Observed MW: 250 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.72 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on KDR (pY1175)

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