KDR (pY1175) Antibody

KDR (pY1175) Antibody is a Rabbit Polyclonal antibody against KDR (pY1175). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.

Target	KDR (pY1175)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around Y1175 of human VEGF Receptor 2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35968 (UniProt, ExPASy)
UniProt Secondary AC	A2RRS0, B5A925, C5IFA0, O60723, Q14178
UniProt Entry Name	VGFR2_HUMAN
Gene Symbol	KDR
GeneID	3791
NCBI Accession	NP_002244.1
KEGG	hsa:3791
String	9606.ENSP00000263923
Molecular Weight	Calculated MW: 152 kDa Observed MW: 230 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	1.72 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on KDR (pY1175)

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