Kelch-Like ECH-Associated Protein 1 (KEAP1) Antibody
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Catalogue No: abx025343
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-Like ECH-Associated Protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Research Articles on Kelch-Like ECH-Associated Protein 1 (KEAP1)
| Target | Kelch-Like ECH-Associated Protein 1 (KEAP1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 422-449 amino acids from human KEAP1. |
| Isotype | IgM Kappa |
| Form | Liquid |
| Purification | Purified Mouse Monoclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q14145 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KPD5, Q6LEP0, Q8WTX1, Q9BPY9 |
| UniProt Entry Name | KEAP1_HUMAN |
| Gene Symbol | KEAP1 |
| GeneID | 9817 |
| OMIM | 606016 |
| HGNC | 23177 |
| KEGG | hsa:9817 |
| Ensembl | ENSG00000079999 |
| String | 9606.ENSP00000171111 |
| Molecular Weight | Calculated MW: 69.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig KEAP1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |