Keratin, Type II Cytoskeletal 5 (KRT5) Antibody

The protein encoded by this gene is a member of the keratin gene family.The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues.This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14.Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex.The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Target	Keratin, Type II Cytoskeletal 5 (KRT5)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CK5 (AA: 316-590) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P13647 (UniProt, ExPASy)
UniProt Secondary AC	Q6PI71, Q6UBJ0, Q8TA91
UniProt Entry Name	K2C5_HUMAN
Gene Symbol	KRT5
GeneID	3852
OMIM	131760
HGNC	6442
KEGG	hsa:3852
Ensembl	ENSG00000186081
String	9606.ENSP00000252242
Molecular Weight	62.3 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Keratin, Type II Cytoskeletal 5 (KRT5)

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