Proliferation Marker Protein Ki-67 (MKI67) Antibody
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Catalogue No: abx139747
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US$333.50
(Size: 0.1 mg)
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Datasheet SDS
Proliferation Marker Protein Ki-67 (MKI67) Antibody is a Mouse Monoclonal against Proliferation Marker Protein Ki-67 (MKI67). Proliferation Marker Protein Ki-67 (MKI67) is a highly protease-sensitive nuclear protein expressed in two isoforms (345 kDa and 395 kDa). It is essential for cell proliferation and is detected in G1, S, G2 and M phase, whereas it is absent in cells which are in G0 phase and it is not associated with DNA repair processes.It is used for detection of proliferating cells, used in tumor diagnostics and is commonly used as a prognostic factor in cancer studies.
Research Articles on Proliferation Marker Protein Ki-67 (MKI67)
| Target | Proliferation Marker Protein Ki-67 (MKI67) |
| Research Area | Tumor Immunity, Reproductive Science |
| Clonality | Monoclonal |
| Clone | F403 |
| Reactivity | Human, Cow |
| Tested Applications | WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | IF/ICC: 1 μg/ml, FCM: 1-5 µg/ml. Not tested in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Nuclei of the Hodgkin lymphoma cell line L428. |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Storage | Store at 2-8°C. Do not freeze. |
| Shelf Life | The shelf life is at least 24 months. |
| UniProt Primary AC | P46013 (UniProt, ExPASy) |
| Gene Symbol | MKI67 |
| GeneID | 4288 |
| KEGG | hsa:4288 |
| String | 9606.ENSP00000357643 |
| Buffer | PBS, containing 15 mM sodium azide. |
| Specificity | This antibody recognizes antigen, a non-histone nuclear protein expressed exclusively in proliferating cells. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |